Formation of dependence on anxiolytics

There is nothing surprising that powerful anxiolytic drugs, such as Xanax, Valium and other drugs based on them contribute to the formation of dependence in patients. Most often, it occurs in cases where the body was initially weakened and when the duration of treatment was too long, exceeding the period of several weeks. In this case, treatment for dependence is a common practice, available to every patient, so despair and panic are not worth it. We can rightly call this effect a kind of “payment” for getting rid of panic attacks and normalizing the sleep regime. Formation of dependence on anxiolytics

The problem of drug dependence to tranquilizers is treated by experts ambiguously. Most authors agree that its risk is directly proportional to the duration of treatment with tranquilizers. The emergence of dependence on benzodiazepines, including Lorazepam, is especially likely. Other remedies are also dangerous in this regard, especially those a feature of which is the development of euphoria.

Withdrawal syndrome influences the occurrence of physical dependence. Its manifestations are gastrointestinal disorders, sweating, tremor, drowsiness, dizziness, headache, intolerance of sharp sounds and smells, tinnitus, irritability, anxiety, insomnia, depersonalization (a sense of loss of oneself and experience of a lack of emotional involvement in relationships to relatives, to work, etc.). As a rule, it is not very severe. The severity and duration of withdrawal disorders can be underestimated and mistakenly taken for neurotic manifestations of the patient’s illness. Examples of long-term (months and even years) use of benzodiazepines are not uncommon without the difficulties of subsequent cancellation, which is facilitated by a certain tactic of treatment and discontinuation of the drug. To prevent abstinence with long-term treatment, lower doses, fractional short courses of therapy should be used, and cancellation should be performed within 1-2 months on the background of psychotherapy or placebo. It may be recommended to replace the short-acting for a long-acting drug in equivalent doses, and the dose reduction rate should be about 25% for every quarter of the cancellation period. Long-term treatment (with good tolerability and lack of tolerance) is possible in elderly patients who, in small doses, take benzodiazepines for symptomatic relief.

In any case, the drug should be taken with caution. Be sure to follow the dosage: this will not help you eliminate the risk of dependence completely but it will greatly facilitate the symptoms of subsequent treatment.

Treatment for the compulsive disorder syndrome with Xanax

Treatment for the compulsive disorder syndrome In the neurosis of compulsive states, apart from all sorts of obsessive fears, experiences, and obsessions, asthenic, and hypochondriac syndromes are common.

Symptoms of obsessive-compulsive disorder

The neurosis of compulsive states is relatively less common than neurasthenia and hysteria. The disease is characterized by the fact that obsessive symptoms of pronounced phobias, as a rule, practically impose all of its clinical pictures and that the obsessive formations in such cases are the source of decompensation. With obsessive-compulsive disorder, obsessive phenomena are presented particularly clearly. The volume of consciousness does not often show a noticeable change. The degree of critical attitude is highest and the elements of the struggle are most pronounced. Patients outside and even during repeated attacks are often quite active, gathered, and try not to detect the presence of obsessions.

If some of the phobias in the obsessive-compulsive state are mostly found in an isolated form, then others appear in different combinations, with the primary phobia leading to the development of neurotic states of secondary, tertiary, etc. obsessive fears in the dynamics. So, for example, cardio phobia causes the appearance of claustrophobia, agoraphobia or to the primarily emerging lyssophobia, an obsessive phobia of sharp objects joins.

Rare, but very typical clinical manifestations of obsessive-compulsive disorder neuroses are obsessive thoughts, memories, doubts, movements and actions that, in addition to the compulsive component, are characterized by a consciousness of their soreness and a critical attitude toward them.

One of the most common types of obsessions are rituals. Rituals are obsessive movements and actions that are always accompanied by obsessive doubts and fears. They are produced by patients in spite of reason to prevent imaginary misfortune and have protective character. Obsessions can occur in different combinations of the same patient. It should be noted that in a wide clinical practice, there is often a combination of phobias with obsessions, i.e. it is a question of various variants of the obsessive-phobic or phobic-obsessive syndrome.

Treatment of obsessive-compulsive disorder

With obsessive-compulsive disorder, preference is given to drugs with a stronger general effect, for example, Alprazolam derivatives, including Xanax and its analogs, available in pharmacies to a wide range of customers.

The drug Alprazolam for the treatment of obsessive-compulsive disorder has an anxiolytic, moderate antidepressant effect, an anticonvulsant and weak hypnotic effect. It has proven high efficiency and is popular. When ingested, it is well absorbed, quickly removed, but with use, care should be taken to prevent the development of dependence.

Side effects of anti-anxiety and safety problems in their use

In general, tranquilizers, unlike other psychotropic drugs (antipsychotics, antidepressants) are characterized by the absence of serious side effects and good tolerability. Specialists distinguish the following main side effects:

  • hypersedation – dose-dependent daytime sleepiness, decreased wakefulness, impaired coordination of attention, forgetfulness, etc.
  • miorelaxation – relaxation of skeletal muscles, manifested by general weakness, weakness in individual muscle groups
  • “behavioral toxicity” – an easy disruption of cognitive functions and psychomotor skills, manifested even in small doses and detected in neuropsychological testing
  • “paradoxical” reactions – increased aggression and agitation (excited state), sleep disorders, usually passing spontaneously or after a dose reduction
  • mental and physical dependence that occurs with prolonged use (6-12 months continuously), the manifestations of which resemble a neurotic anxiety.

These side effects are most common in benzodiazepines, especially Xanax and others from the pharmacies, which can also cause arterial hypotension (especially with parenteral administration), dry mouth, dyspepsia (nausea, vomiting, diarrhea or constipation), increased appetite during the food intake, dysuria (urinary disorders), violation of sexual desire and potency. Benzodiazepines can increase intraocular pressure, so it is contraindicated in closed-angle glaucoma. With long-term use, tolerance is possible. Allergic reactions are rare.

In terms of frequency, lethargy and drowsiness are leading, occurring in about 10% of cases, including the next day within the framework of “residual events” after the evening reception of the drug on the eve. In 5-10 times, there are fewer dizziness and ataxia (violation of coordination of movements) associated with muscle relaxation. However, in the elderly people, these side effects are increasing. In connection with these properties, a contraindication to the use of tranquilizers is myasthenia gravis. Side effects of anti-anxiety

Deepening sleep and myorelaxation caused by tranquilizers cause such a contraindication to their use, as a syndrome of nocturnal sleep apnea – long respiratory pauses in sleep, usually occurring in snoring patients. In this case, hypoxia takes place, the development of myocardial ischemia is possible. Tranquilizers make awakening difficult when breathing stops and relaxing the muscles of the soft palate, sagging and obstructing the flow of air into the larynx and further, into the trachea, leads to aggravation of hypoxia. In this regard, it is appropriate to recall the old recommendation to refrain from using any sleeping pills in snoring patients.

There can appear an increased aggressiveness as a manifestation of “paradoxical” reactions and, therefore, it is recommended to take this drug for not more than 10 days only as a hypnotic. Strengthening aggressiveness or agitation can be difficult to relate clearly to the use of tranquilizers. It can be a manifestation of the course of the disease and not a side effect of the drugs under consideration.

In connection with the adverse effect on the intrauterine fetus, anxiolytics are contraindicated in pregnancy. Tranquilizers, especially benzodiazepines, easily penetrate the placenta. Tranquilizers penetrate into breast milk.

Using Xanax during pregnancy

Surely, you’ve paid attention to the fact that drugs from the group of anti-anxiety are quite dangerous with regard to side effects but this is due to their powerful effect on the body. If there were no side effects, Xanax would have enjoyed frenzied popularity in short term. Still, it is rightfully considered one of the best in its group, along with Ativan and other drugs.

Taking the drug

Is it possible to take this medicine to pregnant women and what to do if the pregnancy occurred while taking the drug? First of all, remember that the use of Xanax, despite its availability in pharmacies, is not recommended for pregnant women, except for situations when its use is necessary. Only a doctor can determine with absolute accuracy how much Xanax you use can to do less harm than good, and vice versa.Using Xanax during pregnancy

If pregnancy occurs during the period of active treatment with Xanax, immediately stop taking the pills and see a doctor. If this is not possible, just stop taking the drug. Try to protect yourself during treatment, regularly check the presence of pregnancy with accurate tests: the less impact there is on the child the better.

The danger

Why is it so dangerous? It has been scientifically proven that the effect of Alprazolam, the main component of Xanax, is toxic on the fetus. It can increase the risk of the appearance of defects in the internal organs of the child if the mother will take the medicine at the beginning of pregnancy. The particularly pronounced effect is carried out in the 1 trimester of the entire gestation period. If you continue to take Xanax for all 9 months or most of the time, a child can be born with drug dependence. This means that the baby will have to go through the cleansing of the body, this is a very difficult period and it is extremely dangerous for the newborn. Also, the drug is able to influence the nervous system because of its powerful relaxing properties. Even in the case of emergency, if the birth should occur in the near future, Xanax is not recommended, as the use before the birth can cause a lot of negative effects, including problems with muscle tone, body temperature and negative impact on reflexes.

At the time when a woman is breastfeeding, the drug can get into breast milk: try to exclude the ingestion of such milk into the baby’s body to avoid the occurrence of drowsiness and other consequences.

Carefully ensure that the drug is stored in a place inaccessible to the child: taking Xanax by a minor patient can lead to bad consequences. Please note: pregnant women, infants, and children under 6 years are not allowed to take the drug, but children over 6 years can use Xanax for treatment under the supervision of a doctor. Take care of your child’s health; do not use drugs that can harm it!